Bioanalytical and Metabolism services
Arcinova provides comprehensive bioanalytical services that complement drug discovery and development needs from preclinical development through to market. Our team can develop, validate and implement bioanalytical LC-MS assays for small and large molecule drugs, generics and biomarkers. We can also synthesise stable labelled standards.
Our services, individually detailed below, can be provided either on a standalone basis or as part of an integrated service offering.
The Arcinova bioanalysis team are experienced in the development, validation, application and technology transfer of LC, UPLC, GC and ion chromatography based assays.
Inductively Coupled Plasma - Mass Spectrometry [ICP-MS]
ICP-MS allows for the rapid and sensitive quantification of elements in biological matrices or to assess elemental impurities in Active Pharmaceutical Ingredients (APIs).
Gas Chromatography - Mass Spectrometry [GC-MS]
GC-MS allows for the rapid and sensitive quantification of volatile drugs, metabolites and biomarkers in biological matrices.
Accurate Mass Spectrometry
Identification of unknowns, for example API impurities or drug metabolites, is a frequent challenge.
In Vitro Services
Arcinova can conduct in vitro testing of pharmaceuticals to support safety, efficacy or molecule selection.
Metabolite Identification Studies
The identification of drug metabolites is an essential part of the drug discovery and development process.