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14C Radiolabelling

  • Custom synthesis of 14C labelled compounds to support pre-clinical ADME studies 
  • GMP synthesis of 14C labelled compounds for human AME studies 
  • Expertise and facilities for handling labelled gases and volatiles including Carbon Dioxide, Carbon Monoxide and Methyl Iodide. 

Projects can be supported either by separate complete syntheses of non-clinical and clinical batches, or by synthesis of a pre-clinical intermediate, which can be used to prepare non-clinical and clinical batches. This second approach can avoid the need for a re-synthesis, saving both time and cost when providing labelled material for the hAME study.

 

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